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D. Palmoplantar Keratodermas: Part 2 - Syndromic PPKs

D. Palmoplantar Keratodermas: Part 2 - Syndromic PPKs

#skin #keratin #ichthyosis #keratin filaments #keratinization #skindisease #skindiseases #skincondition #skincare Link for Joining the Channel: https://www.youtube.com/channel/UC0GlnmHFUbzONmKqeNOqf4Q/join Introduction - 02:23 Classsification of Non-Syndromic Ichthyosis - 03:02 B1. PPK with Cardiomyopathy - 04:29 B1a. Naxos Syndrome - 05:55 B1b. Carvajal-Huerta Syndrome - 08:42 B2. PPK with Hearing Impairment - 15:16 B2a. Vohwinkel Syndrome - 17:22 B2b. Bart-Pumphrey Syndrome - 22:15 B2c. Mitochondrial PPK and Hearing Impairment - 23:18 B3. PPK with Malignancies - 25:53 B3a. Huriez Syndrome - 26:52 B3b. Tylosis with Oesophagial Cancer / Howell-Evans Syndrome - 29:06 B4. PPK with Ectodermal Dysplasias - 32:31 B4a. Clouston Syndrome - 33:00 B4b. Odonto-Onycho-Dermal Dysplasia - 35:13 B4c. Papillon-Lefevre Syndrome - 37:11 B4e. Olmsted Syndrome - 40:18 B5. PPK with Eye Involvement - 45:44 B5a. Oculocutaneous Tyrosinemia [Tyrosinemia type II] - 45:53 B6. PPK with CNS Involvement - 48:58 Approach to Syndromic PPKs - 49:58 Summary of genetic mutations in Syndromic PPKs - 52:00 Further Reading - 53:05 Membership to the Channel - 53:21 End - 55:00 Further Reading: 1. Chapter 63 – Inherited Disorders of Cornification – Oji V et al. In: Rooks Textbook of Dermatology, 10ed. Pg-63.1, Griffiths C et al. 2. Chapter 58 – Palmoplantar Keratodermas. In: Bolognia’s Dermatology, 5ed. Pg-931, Metze D et al. 3. Chapter 48 – Inherited Palmoplantar Keratodermas. In: Fitzpatrick’s Dermatology, 9ed. Pg-816, Samuelov L, Sprecher E.

20 2025-10-17
Context Engineering for AI Agents with LangChain and Manus

Context Engineering for AI Agents with LangChain and Manus

Join us for a deep dive into context engineering – the critical practice that determines how well your AI agents perform in production. Lance Martin from LangChain and Manus co-founder Yichao "Peak" Ji share battle-tested strategies for managing context windows, optimizing performance, and building agents that scale. Peak was recently named one of MIT's Innovators Under 35 for his work on AI agents. Here, we cover Manus's context engineering approach. Strategies include: (1) **Context reduction** via dual-form tool results (full/compact) with policy-based compaction and schema-driven summarization; (2) **Context offloading** through layered action spaces (function calling → sandbox utils → packages/APIs) with filesystem-based state management and shell utilities instead of vectorstore indexing; (3) **Context isolation** using minimal sub-agents (planner, knowledge manager, executor) with agent-as-tool paradigm and constrained decoding for schema-based inter-agent communication. 📊 Access the Presentations: Lance Martin's slides (LangChain): https://docs.google.com/presentation/d/16aaXLu40GugY-kOpqDU4e-S0hD1FmHcNyF0rRRnb1OU/edit?slide=id.p#slide=id.p Yichao "Peak" Ji's slides (Manus): https://drive.google.com/file/d/1QGJ-BrdiTGslS71sYH4OJoidsry3Ps9g/view?usp=sharing Ready to start building reliable agents? Sign up for LangSmith, our agent observability & evals platform: https://www.langchain.com/langsmith/?utm_medium=social&utm_source=youtube&utm_campaign=q4-2025_meetup-manus_co Chapters 0:01:00 Introduction to context engineering 0:12:00 Why context engineering in Manus 0:15:00 Context reduction in Manus 0:19:20 Context isolation in Manus 0:22:17 Context offloading in Manus 0:29:00 Avoid context over-engineering 0:31:00 Q&A: Explain sandbox utils in Manus 0:31:55 Q&A: Indexing (vectorstore) vs just using files 0:32:50 Q&A: Memory in Manus 0:34:30 Q&A: Manus and The Bitter Lesson 0:36:44 Q&A: Data format 0:37:45 Q&A: Summarization tips 0:40:00 Q&A: Sub-agents as tools 0:43:57 Q&A: Model choice 0:46:20 Q&A: Tool selection 0:49:48 Q&A: Planning 0:53:35 Q&A: Guardrails 0:55:39 Q&A: Evals 0:57:15 Q&A: Using RL

34 2025-10-17
5 BEST AI Businesses To Start before 2026 (For Beginners)

5 BEST AI Businesses To Start before 2026 (For Beginners)

📌 Grab for FREE HubSpot’s AI-Powered Viral Toolkit — 15 expert prompts + 50 proven hooks to scale your brand in 2025 - https://clickhubspot.com/6df559 00:00 - Intro 01:49 - #1 Idea 6:15 - #2 Idea 9:27- #3 Idea 12:28 - #4 Idea 15:19- #5 Idea Links: 📩 Follow my Newsletter: https://siliconvalleygirl.beehiiv.com/subscribe 🔗 My Instagram: https://www.instagram.com/siliconvalleygirl/ 📌 My Companies & Products: https://Marinamogilko.co 📹 Video brainstorming, research, and project planning - all in one place - https://partner.spotterstudio.com/ideas-with-marina 💻 Resources that helps my team and me grow the business: - Email & SMS Marketing Automation - https://your.omnisend.com/marina - AI app to work with docs and PFDs - https://www.chatpdf.com/?via=marina 📱Develop your YouTube with AI apps: - AI tool to edit videos in a minutes https://get.descript.com/fa2pjk0ylj0d - Boost your view and subscribers on YouTube - https://vidiq.com/marina - #1 AI video clipping tool - https://www.opus.pro/?via=7925d2 💰 Investment Apps: - Top credit cards for free flights, hotels, and cash-back - https://www.cardonomics.com/i/marina - Intuitive platform for stocks, options, and ETFs - https://a.webull.com/Tfjov8wp37ijU849f8 ⭐ Download my English language workbook - https://bit.ly/3hH7xFm I use affiliate links whenever possible (if you purchase items listed above using my affiliate links, I will get a bonus). #ai

39 2025-10-17
MAU RASAKAN GURIHNYA BISNIS KULINER⁉️GAK PERLU SKILL GAK BUKA RESTORAN JUAL RIBUAN NASI BOX SEHARI‼️

MAU RASAKAN GURIHNYA BISNIS KULINER⁉️GAK PERLU SKILL GAK BUKA RESTORAN JUAL RIBUAN NASI BOX SEHARI‼️

Inspirasi sukses, inspirasi bisnis, dan inspirasi kehidupan dari Bung Cahyo, beliau adalah seorang pengusaha Nasi Box dan saat ini menobatkan dirinya sebagai Raja Nasi Box Indonesia. Gelar tersebut layak disandangnya, karena ribuan Nasi Box Bung Cahyo di bawah naungan Merk Ayam Goreng Tulang Lunak (AGTL) Bu Nanik sudah melegenda, dan saat ini merajai bisnis Nasi Box di Indonesia. Saat ini bung cahyo mengelola http://Www.nasiboxmastery.com Bung Cahyo berbagai rahasia bagaimana memulai bisnis Nasi Box, bahkan bagi ibu-ibu rumah tangga dan emak-emak yang tidak jago masa bisa memulai bisnis Nasi Box dengan order ribuan setiap kali pesan. Ikuti kisah inspiratif Bung Cahyo dalam segmen Bicara Profesi hanya di Channel Youtube Dr. Demul!! #bicaraprofesi #inspirasibisnis #inspirasisukses #inspirasikehidupan #inspirasi #inspirational #inspiration #podcast #podcasts #podcastindonesia #bicaraprofesi #thefounders #nasibox #nasiboxmurah #nasiboxhalal #nasiboxjakarta #makanan #kuliner #food #makananenak #makananindonesia #cemilan #makan #makanankekinian #jajanan #enak #kulinerindonesia #indonesia #makanansehat #instafood #minuman #kulinerjakarta #foodie #jajanankekinian #makanenak #viral #snack #foodporn #jakarta #frozenfood #kulinerbandung #makananpedas #masakan #kulinernusantara #cemilanenak #foodstagram #masakanrumahan #makanmakan #makananviral #kulinersurabaya #bandung #murah #halal #gofood #homemade #cemilankekinian #makananhits #resepmasakan #foodies #resep #foodphotography #indonesianfood #makananringan #dirumahaja #kue #sehat #jajan #makananmurah #wisatakuliner #camilan #catering #dessert #surabaya #reseprumahan #masak #yummy #makansianggratis #makansiangbergizi #makansiang #programprabowogibran #programgibran #prabowo #prabowosubianto #prabowogibran2024 #gibran #gibranrakabumingraka #makansiangbergizi #makansianggratis #bagibagimakan #magnetrezeki #magnetrezekionline #magnetrezekinasrullah #rahasiamagnetrezeki #sedekah #sedekahberkah #sedekahjumat #sedekahbersama #sedekahsiang #sedekahmakanan #shintaeyong #shintaeyongmundur #pssi #makananbergizi #makananbergizigratis #astacita #ikn #iknnusantara #ppn12persen #ppn12 #emakemak #emakemakviral #thepowerofemak #thepowerofemakemak #closethedoor #closethedoorclips #closethedoorpodcast #goyanglidah #prazteguh #pwk #usaharumahan #usahasampingan #usahamodalkecil #peluangusaha #bisnisrumahan #usaha #usahaonline #bisnisonline #peluangbisnis #usahakecil #bisnismudah #bisnis #umkm #peluangusahamudah #bisnisanakmuda #bisnismurah #franchisemurah #umkmindonesia #usahamudah #usahakreatif #waralabaindonesia #waralabamakanan #franchisemakanan #bisnishalal #lfl #grosir #waralabamenguntungkan #kemitraankuliner #usahakecilmenengah #bisnisberkah #kemitraanmodalkecil #usahakuliner #indonesia #waralabacepatbalikmodal #usahamuda #usahawaralaba #kulinerindonesia #usahawan #pengusahamuda #promo #reseller #usahamakanan #minumankekinian #usahasendiri #franchiseindonesia #murah #bisnisiburumahtangga #usahamandiri #usahaminuman #bisnispelajar #bisniskuliner #waralabamudah #murahmeriah #franchiseminuman #order #peluangbisnisonline #usahakekinian #minyakgoreng #usahawanmuda #jujur #prabowogibran #prabowo #prabowosubianto #pilpres #gibranrakabumingraka #jokowi #gibran #capres #pemilu #indonesia #partaigerindra #jawatimur #ganjarpranowo #jakarta #adearmando #gerindra #followforfollowback #generasimilenial #fahrihamzah #menhanprabowo #duniapolitik #militer #tolakprabowo #generasizilenial #emakemak #budimansujatmiko #indonesiamaju #asalbukanprabowo #asalbukan #jokowidodo #prabowopresiden #ganjarmahfud #anisbaswedan #gibranrakabuming #dekade #dirumahaja #kaoskaki #kppm #fashionhijab #fashionista #fashionblogger #baju #gamisterbaru #batik #newnormal #sandal #kpop #piyama #tasmurahsurabaya #fashionstyle #fashion #sofa #hiasanpotbunga #bolafutsal #daster #sepatusandalkekinian #sandalmurah #sepatumurah #terusmajubersamaprabowo #fashionable

41 2025-10-16
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